Gundling N, Drews S, Hoedemaker M
Reprod. Domest. Anim. 2015 Dec;50(6):893-900
PMID: 19416488
卵巣嚢腫の治療法として、Ov-synchプログラムとCIDRプログラムを比較し、CIDRプログラムの方が治癒しやすいことを示している。また、繁殖成績も2群を比較すると良いことが分かる。経済性もCIDRプログラムの方が良い。
種々の要因を用い、目的変数も複数使って、ロジスティック回帰分析を実施している。その多くの結果に「治療法」、「嚢腫の大きさ」、「産後50-60日でのBCS」が選択されている。ORは「嚢腫の大きさ」が著しく高く、大きい卵巣嚢腫がとても治りずらいことが示されている。
臨床獣医師向けの解析方法をしているので、参考になる点が多いな。それにしても、卵胞嚢腫と黄体嚢腫を卵巣嚢腫として併せて解析している点がとても気になる。よく牛の直腸検査時にこの2つの診断に頭を悩ますが、治癒にその診断的意義はないという結果もさらっと付与されている。そうだったのかぁ。少し切ない。
Abstract
It was the aim of this field study to evaluate two different protocols of ovulation synchronization for the treatment of ovarian cysts and their effect on reproductive performance in dairy cows. In addition, factors with a possible influence on treatment success and pregnancy outcome as well as costs per pregnancy were analysed. The study was performed with 130 German Holsteins with ovarian cysts diagnosed on days 55 to 60 postpartum. Cows belonging to group 1 (n = 65) received a modified ovsynch protocol [day 0: 0.15 mg cloprostenol (PGF) + 0.02 mg buserelin acetate (GnRH); day 14: PGF; day 16: GnRH]. Group 2 (n = 65) was treated with the conventional ovsynch protocol (day 0: GnRH; day 7: PGF; day 9: GnRH). Timed artificial insemination was performed 20 to 24 h later. Cows without ovarian cysts served as controls. Treatment success (disappearance of the ovarian cyst) after the first ovsynch cycle was higher in group 1 (66.2%) than in group 2 (23.1%, p < 0.05). Reproductive measures in group 1 were comparable with those of the control group and, compared with group 2, were conspicuously better (66.2%, 76.9%, 83.1%, 59.5% vs. 40.0%, 50.7%, 60.0%, 27.5% for cumulative pregnancy rate after treatment cycle 1 to 3 and second service conception rate, respectively, p < 0.05). Overconditioned cows and cows with larger ovarian cysts showed a diminished treatment and pregnancy success. In group 1, costs per pregnancy were only slightly higher than in the control group (group 1: €352.44, group 2: €484.59, control group: €333.77). In conclusion, our results suggest that ovsynch protocols can be used in the treatment of ovarian cysts. The modified ovsynch protocol led to a better cure rate as well as a better reproductive performance, and was economically beneficial compared with a conventional ovsynch protocol.