Pothmann H, Prunner I, Wagener K, Jaureguiberry M, de la Sota RL, Erber R, Aurich C, Ehling-Schulz M, Drillich M
Theriogenology 2015 May;83(8):1249-53
PMID: 25670153
Abstract
The objectives of this study were to assess the prevalence of subclinical endometritis and the presence of common uterine pathogens in repeat breeder cows. A total of 121 cows with three or more consecutive artificial inseminations without conception and no clinical signs of disease were defined as repeat breeder cows and were enrolled in this trial. Intrauterine samples were collected with the cytobrush technique to determine the prevalence of subclinical endometritis and bacteriologic infections. Blood samples were analyzed for concentrations of progesterone and estradiol in plasma to assess ovarian activity. Furthermore, breed, parity, history of calving and postpartum uterine infection, clinical findings of transrectal palpation, and backfat thickness were analyzed as potential factors for the prevalence of subclinical endometritis in repeat breeder cows. The prevalence of subclinical endometritis in repeat breeder cows was 12.7%; but common uterine pathogens, Escherichia coli and Trueperella pyogenes, were found in only one and three cows, respectively. Ovarian activity was determined in 95.0% of all cows. Recorded variables had no effect on the prevalence of subclinical endometritis in repeat breeder cows. In conclusion, subclinical endometritis and uterine infections linked to common pathogens were playing a minor role as a cause for repeat breeder cows in this study. Alternative reasons for failure to conceive in these cows are discussed.
Conclusion
This study found that SE, intrauterine infections, or ovarian inactivity was not strongly associated with repeat breeding. On the basis of our present findings, the use of antimicrobials is not indicated and hormonal treatments need further justifications.
Introduction
It has been assumed that bacteriologic findings are _____ and not responsible for the failure of cows to conceive.
coincidental: Referring to events that occur simultaneously, but which are regarded as causally unrelated.(偶然)一致した，符合する.
Beside an affected endometrium as a possible reason for failure to conceive, RBCs may also be associated with _____ function of the ovaries.
impaired: Having a physical or mental disability.障害性の
Materials and methods
Repeat breeder cows were defined as cows with three or more consecutive AIs without conception.
Cows were selected during regular herd visits from the farmers’ herd records (3 and more inseminations). Exclusion criteria were a history of hysterotomy, fetotomy, or severe injuries at parturition. All cows eligible were examined by vaginal examination using a metal speculum and a torch, and by transrectal ultrasonographic assessment of the ovaries.
hysterotomy: incision of the uterus, performed either transabdominally (abdominal h.) or vaginally (vaginal h.) . 子宮切開術, 子宮切開, (特に分娩時の)帝王切開術, 帝王切開
fetotomy: dissection of a dead fetus in utero. Applicable particularly to cows because of the size of the uterus and the opportunity to introduce instruments to the full depth of the fetus.
Effects on the prevalence of SE in RBCs were analyzed by using a binary logistic regression model, including breed, parity (heifers, primiparous, multiparous), BFT (underconditioned, normal, overconditioned), calving assistance (no assistance, moderate assistance = 1–2 persons, severe assistance = >2 persons), and history of postpartum uterine disorder (yes, no) as variables.
ネガティブデータだって貴重な報告。RBの定義は重要。logistic regressionも有意差なくても結果として載せてOK！論文は図表の数じゃない！この論文はtable1~3のみ！でも、論文としては読んでいてあまり面白くなかったなぁ。